2ZZ5

Orotidine Monophosphate Deacarboxylase D70A/K72A double mutant from M. thermoautotrophicum complexed with 6- cyano-UMP

Summary for 2ZZ5

Entry DOI	10.2210/pdb2zz5/pdb
Related	1LOR 1LOS 1LP6 1X1Z 2E6Y 2ZZ1 2ZZ2 2ZZ3 2ZZ4 2ZZ6 2ZZ7
Descriptor	Orotidine 5'-phosphate decarboxylase, 6-cyanouridine 5'-phosphate (3 entities in total)
Functional Keywords	orotidine 5'-monophosphate decarboxylase (odcase), 6-cyanoump omp decarboxylase, ompdc, ompdcase, decarboxylase, lyase, pyrimidine biosynthesis
Biological source	Methanothermobacter thermautotrophicus
Total number of polymer chains	2
Total formula weight	55252.96
Authors	Fujihashi, M.,Pai, E.F. (deposition date: 2009-02-05, release date: 2009-03-24, Last modification date: 2023-11-01)
Primary citation	Fujihashi, M.,Wei, L.,Kotra, L.P.,Pai, E.F. Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase J.Mol.Biol., 387:1199-1210, 2009 Cited by PubMed: 19236876 DOI: 10.1016/j.jmb.2009.02.037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.56 Å)

Structure validation