2ZXC

Ceramidase complexed with C2

Summary for 2ZXC

• Entry DOI: 10.2210/pdb2zxc/pdb
• Descriptor: Neutral ceramidase, ZINC ION, N-[(1R,2R,3E)-2-hydroxy-1-(hydroxymethyl)heptadec-3-en-1-yl]acetamide, ... (7 entities in total)
• Functional Keywords: beta-prism fold surrounded by six alpha helix, hydrolase, lipid metabolism, secreted
• Biological source: Pseudomonas aeruginosa
• Cellular location: Secreted : Q9I596
• Total number of polymer chains: 2
• Total formula weight: 143097.48

Authors

Okano, H.,Inoue, T.,Okino, N.,Kakuta, Y.,Matsumura, H.,Ito, M. (deposition date: 2008-12-22, release date: 2009-02-03, Last modification date: 2024-04-03)

• Primary citation: Inoue, T.,Okino, N.,Kakuta, Y.,Hijikata, A.,Okano, H.,Goda, H.M.,Tani, M.,Sueyoshi, N.,Kambayashi, K.,Matsumura, H.,Kai, Y.,Ito, M.; Mechanistic insights into the hydrolysis and synthesis of ceramide by neutral ceramidase.; J.Biol.Chem., 284:9566-9577, 2009; PubMed: 19088069; DOI: 10.1074/jbc.M808232200

Experimental method

X-RAY DIFFRACTION (2.2 Å)