2ZXA

alpha-L-fucosidase complexed with inhibitor, FNJ-acetyl

Summary for 2ZXA

Entry DOI	10.2210/pdb2zxa/pdb
Related	1hl8 2zwy 2zwz 2ZX5 2ZX6 2ZX7 2ZX8 2ZX9 2ZXB 2ZXD
Descriptor	Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide (3 entities in total)
Functional Keywords	tim barrel, hydrolase
Biological source	Thermotoga maritima
Total number of polymer chains	2
Total formula weight	106638.34
Authors	Wu, H.-J.,Ko, T.-P.,Ho, C.-W.,Lin, C.-H.,Wang, A.H.-J. (deposition date: 2008-12-22, release date: 2009-12-08, Last modification date: 2024-10-23)
Primary citation	Wu, H.J.,Ho, C.W.,Ko, T.P.,Popat, S.D.,Lin, C.H.,Wang, A.H. Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49:337-340, 2010 Cited by PubMed: 19967696 DOI: 10.1002/anie.200905597 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.57 Å)

Structure validation