2ZWL

Human factor viia-tissue factor complexed with highly selective peptide inhibitor

2ZWL の概要

• エントリーDOI: 10.2210/pdb2zwl/pdb
• 分子名称: Factor VII light chain, Factor VII heavy chain, Tissue factor, ... (8 entities in total)
• 機能のキーワード: serine protease, alternative splicing, blood coagulation, calcium, cleavage on pair of basic residues, disease mutation, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydrolase, hydroxylation, pharmaceutical, polymorphism, protease, zymogen, lipoprotein, membrane, palmitate, transmembrane, hydrolase-blood clotting complex, secreted, hydrolase/blood clotting
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Secreted: P08709 P08709; Membrane; Single-pass type I membrane protein: P13726
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 71578.38

構造登録者

Kadono, S.,Sakamoto, A.,Kikuchi, Y.,Oh-Eda, M.,Yabuta, N.,Koga, T.,Hattori, K.,Shiraishi, T.,Haramura, M.,Sato, H.,Ohta, M.,Kozono, T. (登録日: 2008-12-16, 公開日: 2009-01-20, 最終更新日: 2023-11-15)

• 主引用文献: Kadono, S.,Sakamoto, A.,Kikuchi, Y.,Oh-Eda, M.,Yabuta, N.,Koga, T.,Hattori, K.,Shiraishi, T.,Haramura, M.,Sato, H.,Ohta, M.,Kozono, T.; Human factor viia-tissue factor complexed with highly selective peptide inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)