2ZVK

Crystal structure of PCNA in complex with DNA polymerase eta fragment

Summary for 2ZVK

Entry DOI	10.2210/pdb2zvk/pdb
Related	2ZVL 2ZVM
Descriptor	Proliferating cell nuclear antigen, DNA polymerase eta (3 entities in total)
Functional Keywords	dna replication, pcna, clamp, translesion synthesis, tls, dna polymerase, tls polymerase, complex, pip-box, dna polymerase eta, transferase, dna-binding, nucleus, systemic lupus erythematosus, disease mutation, dna damage, dna repair, dna synthesis, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, phosphoprotein, schiff base, xeroderma pigmentosum
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus: P12004
Total number of polymer chains	6
Total formula weight	93911.10
Authors	Hishiki, A.,Hashimoto, H.,Hanafusa, T.,Kamei, K.,Ohashi, E.,Shimizu, T.,Ohmori, H.,Sato, M. (deposition date: 2008-11-11, release date: 2009-02-10, Last modification date: 2023-11-01)
Primary citation	Hishiki, A.,Hashimoto, H.,Hanafusa, T.,Kamei, K.,Ohashi, E.,Shimizu, T.,Ohmori, H.,Sato, M. Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen J.Biol.Chem., 284:10552-10560, 2009 Cited by PubMed: 19208623 DOI: 10.1074/jbc.M809745200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation