2ZVK

Crystal structure of PCNA in complex with DNA polymerase eta fragment

2ZVK の概要

• エントリーDOI: 10.2210/pdb2zvk/pdb
• 関連するPDBエントリー: 2ZVL 2ZVM
• 分子名称: Proliferating cell nuclear antigen, DNA polymerase eta (3 entities in total)
• 機能のキーワード: dna replication, pcna, clamp, translesion synthesis, tls, dna polymerase, tls polymerase, complex, pip-box, dna polymerase eta, transferase, dna-binding, nucleus, systemic lupus erythematosus, disease mutation, dna damage, dna repair, dna synthesis, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, phosphoprotein, schiff base, xeroderma pigmentosum
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Nucleus: P12004
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 93911.10

構造登録者

Hishiki, A.,Hashimoto, H.,Hanafusa, T.,Kamei, K.,Ohashi, E.,Shimizu, T.,Ohmori, H.,Sato, M. (登録日: 2008-11-11, 公開日: 2009-02-10, 最終更新日: 2023-11-01)

• 主引用文献: Hishiki, A.,Hashimoto, H.,Hanafusa, T.,Kamei, K.,Ohashi, E.,Shimizu, T.,Ohmori, H.,Sato, M.; Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen; J.Biol.Chem., 284:10552-10560, 2009; PubMed: 19208623; DOI: 10.1074/jbc.M809745200

実験手法

X-RAY DIFFRACTION (2.7 Å)