2ZV9

Lyn Tyrosine Kinase Domain-PP2 complex

2ZV9 の概要

• エントリーDOI: 10.2210/pdb2zv9/pdb
• 関連するPDBエントリー: 2ZV7 2ZV8 2ZVA
• 分子名称: Tyrosine-protein kinase Lyn, 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE (3 entities in total)
• 機能のキーワード: lyn kinase pp2, alternative splicing, atp-binding, kinase, lipoprotein, myristate, nucleotide-binding, palmitate, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, transferase, tyrosine-protein kinase
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Cell membrane (By similarity): P25911
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32113.42

構造登録者

Williams, N.K.,Rossjohn, J. (登録日: 2008-11-04, 公開日: 2008-11-11, 最終更新日: 2023-11-01)

• 主引用文献: Williams, N.K.,Lucet, I.S.,Klinken, S.P.,Ingley, E.,Rossjohn, J.; Crystal Structures of the Lyn Protein Tyrosine Kinase Domain in Its Apo- and Inhibitor-bound State; J.Biol.Chem., 284:284-291, 2009; PubMed: 18984583; DOI: 10.1074/jbc.M807850200

実験手法

X-RAY DIFFRACTION (2.76 Å)