2ZTH

Crystal structure of holo form of rat catechol-o-methyltransferase

2ZTH の概要

• エントリーDOI: 10.2210/pdb2zth/pdb
• 関連するPDBエントリー: 1vid
• 分子名称: Catechol O-methyltransferase, MAGNESIUM ION, S-ADENOSYLMETHIONINE, ... (4 entities in total)
• 機能のキーワード: s-adenosylmethionine dependent methyltransferase, alternative initiation, catecholamine metabolism, cell membrane, cytoplasm, magnesium, membrane, metal-binding, methyltransferase, neurotransmitter degradation, phosphoprotein, s-adenosyl-l-methionine, signal-anchor, transferase, transmembrane
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats)
• 細胞内の位置: Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25339.27

構造登録者

Tsuji, E. (登録日: 2008-10-01, 公開日: 2009-01-13, 最終更新日: 2023-11-01)

• 主引用文献: Tsuji, E.,Okazaki, K.,Isaji, M.,Takeda, K.; Crystal structures of the Apo and Holo form of rat catechol-O-methyltransferase; J.Struct.Biol., 165:133-139, 2009; PubMed: 19111934; DOI: 10.1016/j.jsb.2008.11.012

実験手法