2ZOF

Crystal structure of mouse carnosinase CN2 complexed with MN and bestatin

2ZOF の概要

• エントリーDOI: 10.2210/pdb2zof/pdb
• 関連するPDBエントリー: 2ZOG
• 分子名称: Cytosolic non-specific dipeptidase, MANGANESE (II) ION, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, ... (4 entities in total)
• 機能のキーワード: metallopeptidase, protein-inhibitor complex, cndp2, cndp dipeptidase 2, cn2, bestatin, l-carnosine, carnosinase, mn, carboxypeptidase, hydrolase, metal-binding, metalloprotease, protease, zinc
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Cytoplasm (By similarity): Q9D1A2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 107273.49

構造登録者

Unno, H.,Yamashita, T.,Okumura, N.,Kusunoki, M. (登録日: 2008-05-14, 公開日: 2008-06-10, 最終更新日: 2024-03-13)

• 主引用文献: Unno, H.,Yamashita, T.,Ujita, S.,Okumura, N.,Otani, H.,Okumura, A.,Nagai, K.,Kusunoki, M.; Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2.; J.Biol.Chem., 283:27289-27299, 2008; PubMed: 18550540; DOI: 10.1074/jbc.M801657200

実験手法

X-RAY DIFFRACTION (2.3 Å)