2ZNS

Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with glutamate

Summary for 2ZNS

• Entry DOI: 10.2210/pdb2zns/pdb
• Related: 2ZNR 2ZNU
• Descriptor: Glutamate receptor, ionotropic kainate 1, GLUTAMIC ACID (3 entities in total)
• Functional Keywords: glur5-s1s2, kainate receptor, ligand-binding core, alternative splicing, cell junction, glycoprotein, ion transport, ionic channel, membrane, phosphoprotein, polymorphism, postsynaptic cell membrane, rna editing, synapse, transmembrane, transport, membrane protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P39086
• Total number of polymer chains: 1
• Total formula weight: 29240.57

Authors

Unno, M.,Sasaki, M.,Ikeda-Saito, M. (deposition date: 2008-05-01, release date: 2009-05-05, Last modification date: 2023-11-01)

• Primary citation: Unno, M.,Shinohara, M.,Takayama, K.,Tanaka, H.,Teruya, K.,Doh-Ura, K.,Sakai, R.,Sasaki, M.,Ikeda-Saito, M.; Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors.; J.Mol.Biol., 413:667-683, 2011; PubMed: 21893069; DOI: 10.1016/j.jmb.2011.08.043

Experimental method

X-RAY DIFFRACTION (2 Å)