2ZNH

Crystal Structure of a Domain-Swapped Serpin Dimer

2ZNH の概要

• エントリーDOI: 10.2210/pdb2znh/pdb
• 分子名称: Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: domain-swap, blood coagulation, disease mutation, glycoprotein, heparin-binding, protease inhibitor, secreted, serine protease inhibitor, thrombophilia, blood clotting
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Secreted, extracellular space: P01008
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 100626.18

構造登録者

Yamasaki, M.,Huntington, J.A. (登録日: 2008-04-25, 公開日: 2008-10-21, 最終更新日: 2023-11-01)

• 主引用文献: Yamasaki, M.,Li, W.,Johnson, D.J.,Huntington, J.A.; Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization; Nature, 455:1255-1258, 2008; PubMed: 18923394; DOI: 10.1038/nature07394

実験手法