2ZMC
Crystal structure of human mitotic checkpoint kinase Mps1 catalytic domain apo form
Summary for 2ZMC
Entry DOI | 10.2210/pdb2zmc/pdb |
Related | 2ZMD |
Descriptor | Dual specificity protein kinase TTK, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL (3 entities in total) |
Functional Keywords | kinase, mps1, mitosis, atp-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, tyrosine-protein kinase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 44658.78 |
Authors | Chu, M.L.H.,Chavas, L.M.G.,Douglas, K.T.,Eyers, P.A.,Tabernero, L. (deposition date: 2008-04-16, release date: 2008-05-13, Last modification date: 2023-11-01) |
Primary citation | Chu, M.L.,Chavas, L.M.,Douglas, K.T.,Eyers, P.A.,Tabernero, L. Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125. J.Biol.Chem., 283:21495-21500, 2008 Cited by PubMed: 18480048DOI: 10.1074/jbc.M803026200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.14 Å) |
Structure validation
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