2ZJW

Crystal structure of human CK2 alpha complexed with Ellagic acid

2ZJW の概要

• エントリーDOI: 10.2210/pdb2zjw/pdb
• 分子名称: Casein kinase II subunit alpha, 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione (3 entities in total)
• 機能のキーワード: protein-inhibitor complex, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, transferase, wnt signaling pathway
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40780.38

構造登録者

Sekiguchi, Y.,Kinoshita, T.,Nakaniwa, T.,Tada, T. (登録日: 2008-03-11, 公開日: 2009-03-17, 最終更新日: 2023-11-01)

• 主引用文献: Sekiguchi, Y.,Nakaniwa, T.,Kinoshita, T.,Nakanishi, I.,Kitaura, K.,Hirasawa, A.,Tsujimoto, G.,Tada, T.; Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid; Bioorg.Med.Chem.Lett., 19:2920-2923, 2009; PubMed: 19414254; DOI: 10.1016/j.bmcl.2009.04.076

実験手法

X-RAY DIFFRACTION (2.4 Å)