2ZG1

Crystal Structure of Two N-terminal Domains of Siglec-5 in Complex with 6'-Sialyllactose

2ZG1 の概要

• エントリーDOI: 10.2210/pdb2zg1/pdb
• 関連するPDBエントリー: 1O7S 1QFO 2ZG2 2ZG3
• 分子名称: Sialic acid-binding Ig-like lectin 5, N-acetyl-alpha-neuraminic acid (3 entities in total)
• 機能のキーワード: siglec-5 inhibitory receptor, two-domain structure, v-set, c2-set, ig-like domain, sialic acid, 6'-sialyllactose complex, cell adhesion, glycoprotein, immunoglobulin domain, lectin, membrane, polymorphism, transmembrane, immune system-carbohydrate binding protein complex, immune system/carbohydrate binding protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: O15389
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24641.62

構造登録者

Zhuravleva, M.A.,Sun, P.D. (登録日: 2008-01-17, 公開日: 2008-02-05, 最終更新日: 2023-11-01)

• 主引用文献: Zhuravleva, M.A.,Trandem, K.,Sun, P.D.; Structural implications of Siglec-5-mediated sialoglycan recognition; J.Mol.Biol., 375:437-447, 2008; PubMed: 18022638; DOI: 10.1016/j.jmb.2007.10.009

実験手法

X-RAY DIFFRACTION (2.7 Å)