2ZCG

Structure and inhibition of orotidine 5'-phosphate decarboxylase from plasmodium falciparum

2ZCG の概要

• エントリーDOI: 10.2210/pdb2zcg/pdb
• 分子名称: Orotidine 5'-phosphate decarboxylase (2 entities in total)
• 機能のキーワード: tim barrel, decarboxylase, lyase, pyrimidine biosynthesis
• 由来する生物種: Plasmodium falciparum (malaria parasite P. falciparum)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75732.49

構造登録者

Langley, D.B.,Guss, J.M.,Shojaei, M.,Christopherson, R.I. (登録日: 2007-11-08, 公開日: 2008-03-11, 最終更新日: 2023-11-01)

• 主引用文献: Langley, D.B.,Shojaei, M.,Chan, C.,Lok, H.C.,Mackay, J.P.,Traut, T.W.,Guss, J.M.,Christopherson, R.I.; Structure and Inhibition of Orotidine 5'-Monophosphate Decarboxylase from Plasmodium falciparum; Biochemistry, 47:3842-3854, 2008; PubMed: 18303855; DOI: 10.1021/bi702390k

実験手法

X-RAY DIFFRACTION (2.223 Å)