2ZB1
Crystal structure of P38 in complex with biphenyl amide inhibitor
Summary for 2ZB1
Entry DOI | 10.2210/pdb2zb1/pdb |
Related | 2ZAZ 2ZB0 |
Descriptor | Mitogen-activated protein kinase 14, N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide, GLYCEROL, ... (4 entities in total) |
Functional Keywords | serine/threonine protein kinase, map kinase, p38, atp-binding, nucleotide-binding, nucleus, phosphorylation, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 41874.79 |
Authors | Somers, D.O. (deposition date: 2007-10-13, release date: 2008-01-15, Last modification date: 2024-03-13) |
Primary citation | Angell, R.M.,Bamborough, P.,Cleasby, A.,Cockerill, S.G.,Jones, K.L.,Mooney, C.J.,Somers, D.O.,Walker, A.L. Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode Bioorg.Med.Chem.Lett., 18:318-323, 2008 Cited by PubMed: 18006306DOI: 10.1016/j.bmcl.2007.10.076 PDB entries with the same primary citation |
Experimental method |
Structure validation
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