2Z9K
Complex structure of SARS-CoV 3C-like protease with JMF1600
2Z9K の概要
エントリーDOI | 10.2210/pdb2z9k/pdb |
関連するPDBエントリー | 2Z9G 2Z9J 2Z9L |
分子名称 | 3C-like proteinase, DIMETHYL SULFOXIDE, (dimethylamino)(hydroxy)zinc', ... (4 entities in total) |
機能のキーワード | complex, atp-binding, cytoplasm, endonuclease, exonuclease, helicase, hydrolase, membrane, metal-binding, nuclease, nucleotide-binding, nucleotidyltransferase, protease, ribosomal frameshift, rna replication, rna-binding, rna-directed rna polymerase, thiol protease, transferase, transmembrane, zinc, zinc-finger |
由来する生物種 | SARS coronavirus |
細胞内の位置 | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 68318.79 |
構造登録者 | |
主引用文献 | Lee, C.C.,Kuo, C.J.,Hsu, M.F.,Liang, P.H.,Fang, J.M.,Shie, J.J.,Wang, A.H. Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors. Febs Lett., 581:5454-5458, 2007 Cited by PubMed: 17981158DOI: 10.1016/j.febslet.2007.10.048 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.85 Å) |
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