2Z8K
Crystal Structure of Escherichia coli gamma-Glutamyltranspeptidase in Complex with Acivicin
Summary for 2Z8K
Entry DOI | 10.2210/pdb2z8k/pdb |
Related | 2Z8I 2Z8J |
Descriptor | Gamma-glutamyltranspeptidase, (2S)-AMINO[(5S)-3-CHLORO-4,5-DIHYDROISOXAZOL-5-YL]ACETIC ACID, ... (4 entities in total) |
Functional Keywords | acivicin formed a covalent bond with thr391, acyltransferase, glutathione biosynthesis, transferase, zymogen |
Biological source | Escherichia coli More |
Cellular location | Periplasm: P18956 P18956 |
Total number of polymer chains | 4 |
Total formula weight | 119036.56 |
Authors | Wada, K.,Irie, M.,Fukuyama, K. (deposition date: 2007-09-05, release date: 2008-06-24, Last modification date: 2012-04-04) |
Primary citation | Wada, K.,Hiratake, J.,Irie, M.,Okada, T.,Yamada, C.,Kumagai, H.,Suzuki, H.,Fukuyama, K. Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists J.Mol.Biol., 380:361-372, 2008 Cited by PubMed: 18555071DOI: 10.1016/j.jmb.2008.05.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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