2Z7K

tRNA-Guanine transglycosylase (TGT) in complex with 2-Amino-lin-Benzoguanine

2Z7K の概要

• エントリーDOI: 10.2210/pdb2z7k/pdb
• 関連するPDBエントリー: 2BBF 2QZR
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 2,6-diamino-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (5 entities in total)
• 機能のキーワード: tim barrel, glycosyltransferase, metal-binding, queuosine biosynthesis, transferase, trna processing
• 由来する生物種: Zymomonas mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43299.40

構造登録者

Ritschel, T.,Heine, A.,Klebe, G. (登録日: 2007-08-24, 公開日: 2008-08-26, 最終更新日: 2023-11-01)

• 主引用文献: Ritschel, T.,Hoertner, S.,Heine, A.,Diederich, F.,Klebe, G.; Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT; Chembiochem, 10:716-727, 2009; PubMed: 19199329; DOI: 10.1002/cbic.200800782

実験手法

X-RAY DIFFRACTION (1.28 Å)