2Z3Y
Crystal structure of Lysine-specific demethylase1
Summary for 2Z3Y
Entry DOI | 10.2210/pdb2z3y/pdb |
Related | 2EJR 2Z5U |
Descriptor | Lysine-specific histone demethylase 1, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-5-[7,8-DIMETHYL-2,4-DIOXO-5-(3-PHENYLPROPANOYL)-1,3,4,5-TETRAHYDROBENZO[G]PTERIDIN-10(2H)-YL]-2,3,4-TRIHYDROXYPENTYL DIHYDROGEN DIPHOSPHATE (3 entities in total) |
Functional Keywords | chromatin, histone demethylase, nucleosome, transcription, lsd1, lysine-specific, alternative splicing, chromatin regulator, coiled coil, fad, nucleus, oxidoreductase, phosphorylation, repressor, transcription regulation, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O60341 |
Total number of polymer chains | 1 |
Total formula weight | 74571.97 |
Authors | Mimasu, S.,Sengoku, T.,Umehara, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-06-08, release date: 2008-01-01, Last modification date: 2024-03-13) |
Primary citation | Mimasu, S.,Sengoku, T.,Fukuzawa, S.,Umehara, T.,Yokoyama, S. Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A Biochem.Biophys.Res.Commun., 366:15-22, 2008 Cited by PubMed: 18039463DOI: 10.1016/j.bbrc.2007.11.066 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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