2Z3Y
Crystal structure of Lysine-specific demethylase1
2Z3Y の概要
エントリーDOI | 10.2210/pdb2z3y/pdb |
関連するPDBエントリー | 2EJR 2Z5U |
分子名称 | Lysine-specific histone demethylase 1, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4S)-5-[7,8-DIMETHYL-2,4-DIOXO-5-(3-PHENYLPROPANOYL)-1,3,4,5-TETRAHYDROBENZO[G]PTERIDIN-10(2H)-YL]-2,3,4-TRIHYDROXYPENTYL DIHYDROGEN DIPHOSPHATE (3 entities in total) |
機能のキーワード | chromatin, histone demethylase, nucleosome, transcription, lsd1, lysine-specific, alternative splicing, chromatin regulator, coiled coil, fad, nucleus, oxidoreductase, phosphorylation, repressor, transcription regulation, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Nucleus: O60341 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 74571.97 |
構造登録者 | Mimasu, S.,Sengoku, T.,Umehara, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2007-06-08, 公開日: 2008-01-01, 最終更新日: 2024-03-13) |
主引用文献 | Mimasu, S.,Sengoku, T.,Fukuzawa, S.,Umehara, T.,Yokoyama, S. Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A Biochem.Biophys.Res.Commun., 366:15-22, 2008 Cited by PubMed: 18039463DOI: 10.1016/j.bbrc.2007.11.066 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.25 Å) |
構造検証レポート
検証レポート(詳細版)
をダウンロード
![ダウンロード](/newweb/media/icons/dl.png)