2Z2M
Cefditoren-Acylated Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae
Summary for 2Z2M
Entry DOI | 10.2210/pdb2z2m/pdb |
Related | 2Z2L |
Descriptor | Penicillin-binding protein 2X, SULFATE ION, (2R)-2-[(1R)-1-{[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-2-OXOETHYL]-5-[(Z)-2-(4-METHYL-1,3-THIAZOL-5-YL)VINYL]-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID, ... (6 entities in total) |
Functional Keywords | peptidoglycan synthesis, cell wall, penicillin-binding, antibiotics, cefditoren, biosynthetic protein |
Biological source | Streptococcus pneumoniae More |
Cellular location | Cell membrane; Single-pass membrane protein: P59676 P59676 P59676 |
Total number of polymer chains | 6 |
Total formula weight | 149475.32 |
Authors | Yamada, M.,Watanabe, T.,Takeuchi, Y. (deposition date: 2007-05-23, release date: 2007-09-04, Last modification date: 2023-11-01) |
Primary citation | Yamada, M.,Watanabe, T.,Miyara, T.,Baba, N.,Saito, J.,Takeuchi, Y.,Ohsawa, F. Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity Antimicrob.Agents Chemother., 51:3902-3907, 2007 Cited by PubMed: 17724158DOI: 10.1128/AAC.00743-07 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report