2YZ3

Crystallographic Investigation of Inhibition Mode of the VIM-2 Metallo-beta-lactamase from Pseudomonas aeruginosa with Mercaptocarboxylate Inhibitor

Summary for 2YZ3

Entry DOI	10.2210/pdb2yz3/pdb
Descriptor	Metallo-beta-lactamase, ZINC ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	metallo-beta-lactamase, enzyme-inhibitor complex, hydrolase
Biological source	Pseudomonas putida
Total number of polymer chains	2
Total formula weight	57800.20
Authors	Yamaguchi, Y.,Yamagata, Y.,Arakawa, Y.,Kurosaki, H. (deposition date: 2007-05-02, release date: 2008-03-11, Last modification date: 2024-03-13)
Primary citation	Yamaguchi, Y.,Jin, W.,Matsunaga, K.,Ikemizu, S.,Yamagata, Y.,Wachino, J.,Shibata, N.,Arakawa, Y.,Kurosaki, H. Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor. J.Med.Chem., 50:6647-6653, 2007 Cited by PubMed: 18052313 DOI: 10.1021/jm701031n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation