2YY2
Crystal structure of the human Phosphodiesterase 9A catalytic domain complexed with IBMX
Summary for 2YY2
Entry DOI | 10.2210/pdb2yy2/pdb |
Descriptor | High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | catalytic domain, phosphodiesterase, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform PDE9A1: Cell projection, ruffle membrane. Isoform PDE9A2: Cell projection, ruffle membrane. Isoform PDE9A3: Cytoplasm. Isoform PDE9A17: Cytoplasm: O76083 |
Total number of polymer chains | 2 |
Total formula weight | 78755.98 |
Authors | Handa, N.,Shirouzu, M.,Terada, T.,Omori, K.,Kotera, J.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-04-27, release date: 2007-10-30, Last modification date: 2024-08-14) |
Primary citation | Handa, N.,Shirouzu, M.,Terada, T.,Omori, K.,Kotera, J.,Yokoyama, S. Crystal structure of the human Phosphodiesterase 9A catalytic domain. To be Published, |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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