2YY2

Crystal structure of the human Phosphodiesterase 9A catalytic domain complexed with IBMX

Summary for 2YY2

• Entry DOI: 10.2210/pdb2yy2/pdb
• Descriptor: High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: catalytic domain, phosphodiesterase, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Isoform PDE9A1: Cell projection, ruffle membrane. Isoform PDE9A2: Cell projection, ruffle membrane. Isoform PDE9A3: Cytoplasm. Isoform PDE9A17: Cytoplasm: O76083
• Total number of polymer chains: 2
• Total formula weight: 78755.98

Authors

Handa, N.,Shirouzu, M.,Terada, T.,Omori, K.,Kotera, J.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-04-27, release date: 2007-10-30, Last modification date: 2025-04-30)

• Primary citation: Handa, N.,Shirouzu, M.,Terada, T.,Omori, K.,Kotera, J.,Yokoyama, S.; Crystal structure of the human Phosphodiesterase 9A catalytic domain.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)