2YY2

Crystal structure of the human Phosphodiesterase 9A catalytic domain complexed with IBMX

2YY2 の概要

• エントリーDOI: 10.2210/pdb2yy2/pdb
• 分子名称: High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: catalytic domain, phosphodiesterase, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform PDE9A1: Cell projection, ruffle membrane. Isoform PDE9A2: Cell projection, ruffle membrane. Isoform PDE9A3: Cytoplasm. Isoform PDE9A17: Cytoplasm: O76083
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 78755.98

構造登録者

Handa, N.,Shirouzu, M.,Terada, T.,Omori, K.,Kotera, J.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2007-04-27, 公開日: 2007-10-30, 最終更新日: 2025-04-30)

• 主引用文献: Handa, N.,Shirouzu, M.,Terada, T.,Omori, K.,Kotera, J.,Yokoyama, S.; Crystal structure of the human Phosphodiesterase 9A catalytic domain.; To be Published,

実験手法

X-RAY DIFFRACTION (2.8 Å)