2YOE
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with GABA and flurazepam
Replaces: 4A96Summary for 2YOE
Entry DOI | 10.2210/pdb2yoe/pdb |
Related | 2YKS 4A97 4A98 |
Descriptor | CYS-LOOP LIGAND-GATED ION CHANNEL, GAMMA-AMINO-BUTANOIC ACID, Flurazepam (3 entities in total) |
Functional Keywords | transport protein, cys-loop receptor, gaba-a receptor, benzodiazepine |
Biological source | ERWINIA CHRYSANTHEMI |
Cellular location | Cell inner membrane; Multi-pass membrane protein (Probable): P0C7B7 |
Total number of polymer chains | 10 |
Total formula weight | 354427.79 |
Authors | Spurny, R.,Brams, M.,Nury, H.,Legrand, P.,Ulens, C. (deposition date: 2012-10-23, release date: 2012-10-31, Last modification date: 2023-12-20) |
Primary citation | Spurny, R.,Ramerstorfer, J.,Price, K.,Brams, M.,Ernst, M.,Nury, H.,Verheij, M.,Legrand, P.,Bertrand, D.,Bertrand, S.,Dougherty, D.A.,De Esch, I.J.P.,Corringer, P.,Sieghart, W.,Lummis, S.C.R.,Ulens, C. Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines. Proc.Natl.Acad.Sci.USA, 109:E3028-, 2012 Cited by PubMed: 23035248DOI: 10.1073/PNAS.1208208109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.9 Å) |
Structure validation
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