2YOE

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with GABA and flurazepam

Replaces:  4A96

Summary for 2YOE

• Entry DOI: 10.2210/pdb2yoe/pdb
• Related: 2YKS 4A97 4A98
• Descriptor: CYS-LOOP LIGAND-GATED ION CHANNEL, GAMMA-AMINO-BUTANOIC ACID, Flurazepam (3 entities in total)
• Functional Keywords: transport protein, cys-loop receptor, gaba-a receptor, benzodiazepine
• Biological source: ERWINIA CHRYSANTHEMI
• Cellular location: Cell inner membrane; Multi-pass membrane protein (Probable): P0C7B7
• Total number of polymer chains: 10
• Total formula weight: 354427.79

Authors

Spurny, R.,Brams, M.,Nury, H.,Legrand, P.,Ulens, C. (deposition date: 2012-10-23, release date: 2012-10-31, Last modification date: 2023-12-20)

• Primary citation: Spurny, R.,Ramerstorfer, J.,Price, K.,Brams, M.,Ernst, M.,Nury, H.,Verheij, M.,Legrand, P.,Bertrand, D.,Bertrand, S.,Dougherty, D.A.,De Esch, I.J.P.,Corringer, P.,Sieghart, W.,Lummis, S.C.R.,Ulens, C.; Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.; Proc.Natl.Acad.Sci.USA, 109:E3028-, 2012; PubMed: 23035248; DOI: 10.1073/PNAS.1208208109

Experimental method

X-RAY DIFFRACTION (3.9 Å)