2YEN
Solution structure of the skeletal muscle and neuronal voltage gated sodium channel antagonist mu-conotoxin CnIIIC
Summary for 2YEN
Entry DOI | 10.2210/pdb2yen/pdb |
Descriptor | Mu-conotoxin CnIIIC (1 entity in total) |
Functional Keywords | toxin, conotoxin, neurotoxin, amidated c-terminus |
Biological source | Conus consors (Singed cone) |
Total number of polymer chains | 1 |
Total formula weight | 2385.78 |
Authors | Favreau, P.,Benoit, E.,Hocking, H.G.,Carlier, L.,D'hoedt, D.,Leipold, E.,Markgraf, R.,Schlumberger, S.,Cordova, M.A.,Gaertner, H.,Paolini-Bertrand, M.,Hartley, O.,Tytgat, J.,Heinemann, S.H.,Bertrand, D.,Boelens, R.,Stocklin, R.,Molgo, J. (deposition date: 2011-03-28, release date: 2012-02-08, Last modification date: 2023-06-14) |
Primary citation | Favreau, P.,Benoit, E.,Hocking, H.G.,Carlier, L.,D'Hoedt, D.,Leipold, E.,Markgraf, R.,Schlumberger, S.,Cordova, M.A.,Gaertner, H.,Paolini-Bertrand, M.,Hartley, O.,Tytgat, J.,Heinemann, S.H.,Bertrand, D.,Boelens, R.,Stocklin, R.,Molgo, J. A Novel Mu-Conopeptide, Cniiic, Exerts Potent and Preferential Inhibition of Na(V) 1.2/1.4 Channels and Blocks Neuronal Nicotinic Acetylcholine Receptors. Br.J.Pharmacol., 166:1654-, 2012 Cited by PubMed: 22229737DOI: 10.1111/J.1476-5381.2012.01837.X PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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