2Y92

Crystal structure of MAL adaptor protein

Summary for 2Y92

Entry DOI	10.2210/pdb2y92/pdb
Descriptor	TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN,, 2,3-DIHYDROXY-1,4-DITHIOBUTANE (2 entities in total)
Functional Keywords	immune system, toll-like receptor signaling, innate immunity
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm (By similarity): P58753
Total number of polymer chains	1
Total formula weight	16067.36
Authors	Valkov, E.,Stamp, A.,Martin, J.L.,Kobe, B. (deposition date: 2011-02-11, release date: 2011-09-14, Last modification date: 2023-12-20)
Primary citation	Valkov, E.,Stamp, A.,Dimaio, F.,Baker, D.,Verstak, B.,Roversi, P.,Kellie, S.,Sweet, M.J.,Mansell, A.,Gay, N.J.,Martin, J.L.,Kobe, B. Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection. Proc.Natl.Acad.Sci.USA, 108:14879-, 2011 Cited by PubMed: 21873236 DOI: 10.1073/PNAS.1104780108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.01 Å)

Structure validation