2XVT

Structure of the extracellular domain of human RAMP2

Summary for 2XVT

DescriptorRECEPTOR ACTIVITY-MODIFYING PROTEIN 2, CALCIUM ION (3 entities in total)
Functional Keywordsmembrane protein, transmembrane, receptor transport, protein-trafficking, gpcr, crlr, cgrp, adrenomedulin
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMembrane; Single-pass type I membrane protein O60895
Total number of polymer chains6
Total molecular weight65359.17
Authors
Primary citation
Quigley, A.,Pike, A.C.W.,Burgess-Brown, N.,Krojer, T.,Shrestha, L.,Goubin, S.,Kim, J.,Das, S.,Muniz, J.R.C.,Canning, P.,Chaikuad, A.,Vollmar, M.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bountra, C.,Barr, A.J.,Carpenter, E.P.
Structure of the Extracellular Domain of Human Ramp2
To be Published,
Experimental method
X-RAY DIFFRACTION (2.05 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25030.2%0.5%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution