2XUE
CRYSTAL STRUCTURE OF JMJD3
Summary for 2XUE
Entry DOI | 10.2210/pdb2xue/pdb |
Descriptor | LYSINE-SPECIFIC DEMETHYLASE 6B, ZINC ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | oxidoreductase, histone methylase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus (Probable): O15054 |
Total number of polymer chains | 2 |
Total formula weight | 116565.03 |
Authors | Chung, C.,Rowland, P.,Mosley, J.,Thomas, P.J. (deposition date: 2010-10-19, release date: 2011-12-28, Last modification date: 2024-05-08) |
Primary citation | Kruidenier, L.,Chung, C.,Cheng, Z.,Liddle, J.,Che, K.,Joberty, G.,Bantscheff, M.,Bountra, C.,Bridges, A.,Diallo, H.,Eberhard, D.,Hutchinson, S.,Jones, E.,Katso, R.,Leveridge, M.,Mander, P.K.,Mosley, J.,Ramirez-Molina, C.,Rowland, P.,Schofield, C.J.,Sheppard, R.J.,Smith, J.E.,Swales, C.,Tanner, R.,Thomas, P.,Tumber, A.,Drewes, G.,Oppermann, U.,Patel, D.J.,Lee, K.,Wilson, D.M. A Selective Jumonji H3K27 Demethylase Inhibitor Modulates the Proinflammatory Macrophage Response Nature, 488:404-, 2012 Cited by PubMed: 22842901DOI: 10.1038/NATURE11262 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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