2XSQ

Crystal structure of human Nudix motif 16 (NUDT16) in complex with IMP and magnesium

2XSQ の概要

• エントリーDOI: 10.2210/pdb2xsq/pdb
• 分子名称: U8 SNORNA-DECAPPING ENZYME, INOSINIC ACID, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: hydrolase, mrna decapping, mrna turnover, structural genomics consortium, sgc
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Nucleus : Q96DE0
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24321.45

構造登録者

Tresaugues, L.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kol, S.,Kotenyova, T.,Kouznetsova, E.,Moche, M.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,van den Berg, S.,Wahlberg, E.,Weigelt, J.,Nordlund, P. (登録日: 2010-09-29, 公開日: 2010-11-17, 最終更新日: 2023-12-20)

• 主引用文献: Tresaugues, L.,Lundback, T.,Welin, M.,Flodin, S.,Nyman, T.,Silvander, C.,Graslund, S.,Nordlund, P.; Structural Basis for the Specificity of Human Nudt16 and its Regulation by Inosine Monophosphate.; Plos One, 10:31507-, 2015; PubMed: 26121039; DOI: 10.1371/JOURNAL.PONE.0131507

実験手法

X-RAY DIFFRACTION (1.72 Å)