2XNT

Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors

Summary for 2XNT

Entry DOI	10.2210/pdb2xnt/pdb
Related	2BR7 2BR8 2BYN 2BYP 2BYQ 2BYR 2BYS 2C9T 2UZ6 2W8E 2W8F 2W8G 2WN9 2WNC 2WNJ 2WNL 2WZY 2X00 2XNU 2XNV
Descriptor	SOLUBLE ACETYLCHOLINE RECEPTOR, (2S)-2-[(4-CHLOROBENZYL)OXY]-2-PHENYLETHANAMINE, BROMIDE ION (3 entities in total)
Functional Keywords	receptor, choline-binding protein, in-silico screening, ligand-gated ion channels, electrophysiology, cys-loop receptors
Biological source	APLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
Total number of polymer chains	10
Total formula weight	269876.18
Authors	Rucktooa, P.,Akdemir, A.,deEsch, I.,Sixma, T.K. (deposition date: 2010-08-06, release date: 2011-08-24, Last modification date: 2023-12-20)
Primary citation	Akdemir, A.,Rucktooa, P.,Jongejan, A.,Elk, R.V.,Bertrand, S.,Sixma, T.K.,Bertrand, D.,Smit, A.B.,Leurs, R.,De Graaf, C.,De Esch, I.J. Acetylcholine Binding Protein (Achbp) as Template for Hierarchical in Silico Screening Procedures to Identify Structurally Novel Ligands for the Nicotinic Receptors. Bioorg.Med.Chem., 19:6107-, 2011 Cited by PubMed: 21920761 DOI: 10.1016/J.BMC.2011.08.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.21 Å)

Structure validation