2XMC

G117H mutant of human butyrylcholinesterase in complex with fluoride anion

2XMC の概要

• エントリーDOI: 10.2210/pdb2xmc/pdb
• 関連するPDBエントリー: 1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL 2WSL 2XMB 2XMD 2XMG
• 分子名称: CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: hydrolase, glycoprotein
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62298.09

構造登録者

Nachon, F.,Carletti, E.,Wandhammer, M.,Nicolet, Y.,Schopfer, L.M.,Masson, P.,Lockridge, O. (登録日: 2010-07-27, 公開日: 2010-12-01, 最終更新日: 2023-12-20)

• 主引用文献: Nachon, F.,Carletti, E.,Wandhammer, M.,Nicolet, Y.,Schopfer, L.M.,Masson, P.,Lockridge, O.; X-Ray Crystallographic Snapshots of Reaction Intermediates in the G117H Mutant of Human Butyrylcholinesterase, a Nerve Agent Target Engineered Into a Catalytic Bioscavenge; Biochem.J., 434:73-, 2011; PubMed: 21091433; DOI: 10.1042/BJ20101648

実験手法

X-RAY DIFFRACTION (2.4 Å)