2XJB

Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with deoxyguanosine monophosphate and deoxyadenosine triphosphate

2XJB の概要

• エントリーDOI: 10.2210/pdb2xjb/pdb
• 関連するPDBエントリー: 2J2C 2JC9 2JCM 2XCV 2XCW 2XCX 2XJC 2XJD 2XJE 2XJF
• 分子名称: CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: allosteric enzyme, cn-ii, gmp-imp specific nucleotidase, high km 5-prime nucleotidase, hydrolase, metal-binding, nt5c2, nucleotide metabolism, nucleotide-binding, phosphoprotein
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cytoplasm: P49902
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 65120.04

構造登録者

Wallden, K.,Nordlund, P. (登録日: 2010-07-03, 公開日: 2011-03-16, 最終更新日: 2023-12-20)

• 主引用文献: Wallden, K.,Nordlund, P.; Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II; J.Mol.Biol., 408:684-, 2011; PubMed: 21396942; DOI: 10.1016/J.JMB.2011.02.059

実験手法

X-RAY DIFFRACTION (2.3 Å)