2XHB
Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA
Summary for 2XHB
Entry DOI | 10.2210/pdb2xhb/pdb |
Related | 1TGO 1WN7 2VWJ 2VWK |
Descriptor | DNA POLYMERASE, HYPOXANTHINE-CONTAINING DNA, 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', ... (5 entities in total) |
Functional Keywords | transferase-dna complex, replication, exonuclease, dna damage, exo minus, transferase/dna |
Biological source | THERMOCOCCUS GORGONARIUS |
Total number of polymer chains | 3 |
Total formula weight | 101327.66 |
Authors | Killelea, T.,Ghosh, S.,Tan, S.S.,Heslop, P.,Firbank, S.J.,Kool, E.T.,Connolly, B.A. (deposition date: 2010-06-14, release date: 2010-07-21, Last modification date: 2023-12-20) |
Primary citation | Killelea, T.,Ghosh, S.,Tan, S.S.,Heslop, P.,Firbank, S.J.,Kool, E.T.,Connolly, B.A. Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues. Biochemistry, 49:5772-, 2010 Cited by PubMed: 20527806DOI: 10.1021/BI100421R PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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