2XGP

Yeast DNA polymerase eta in complex with C8-2-acetylaminofluorene containing DNA

Summary for 2XGP

• Entry DOI: 10.2210/pdb2xgp/pdb
• Related: 1JIH 2WTF 2XGQ
• Descriptor: DNA POLYMERASE ETA, 5'-D(*GP*TP*GP*GP*AP*TP*GP*AP*G)-3', 5'-D(*CP*8FG*CP*TP*CP*AP*TP*CP*CP*AP*C)-3', ... (5 entities in total)
• Functional Keywords: transferase-dna complex, translesion dna synthesis, dna-binding, dna damage, transferase/dna
• Biological source: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
• Cellular location: Nucleus : Q04049
• Total number of polymer chains: 6
• Total formula weight: 134360.45

Authors

Scheider, S.,Lammens, K.,Schorr, S.,Hopfner, K.P.,Carell, T. (deposition date: 2010-06-07, release date: 2010-11-03, Last modification date: 2023-12-20)

• Primary citation: Schorr, S.,Schneider, S.,Lammens, K.,Hopfner, K.P.,Carell, T.; Mechanism of Replication Blocking and Bypass of Y-Family Polymerase Eta by Bulky Acetylaminofluorene DNA Adducts.; Proc.Natl.Acad.Sci.USA, 107:20720-, 2010; PubMed: 21076032; DOI: 10.1073/PNAS.1008894107

Experimental method

X-RAY DIFFRACTION (2.7 Å)