2XFL

Induced-fit and allosteric effects upon polyene binding revealed by crystal structures of the Dynemicin thioesterase

Summary for 2XFL

• Entry DOI: 10.2210/pdb2xfl/pdb
• Related: 2XEM
• Descriptor: DYNE7 (2 entities in total)
• Functional Keywords: hydrolase, polyketide biosynthesis, enediyne, hot-dog fold
• Biological source: MICROMONOSPORA CHERSINA
• Total number of polymer chains: 8
• Total formula weight: 127040.32

Authors

Liew, C.W.,Sharff, A.,Kotaka, M.,Kong, R.,Sun, H.,Bricogne, G.,Liang, Z.,Lescar, J. (deposition date: 2010-05-26, release date: 2010-10-13, Last modification date: 2023-12-20)

• Primary citation: Liew, C.W.,Sharff, A.,Kotaka, M.,Kong, R.,Sun, H.,Qureshi, I.,Bricogne, G.,Liang, Z.,Lescar, J.; Induced-Fit Upon Ligand Binding Revealed by Crystal Structures of the Hot-Dog Fold Thioesterase in Dynemicin Biosynthesis.; J.Mol.Biol., 404:291-, 2010; PubMed: 20888341; DOI: 10.1016/J.JMB.2010.09.041

Experimental method

X-RAY DIFFRACTION (2.9 Å)