2XDG

Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor.

Summary for 2XDG

DescriptorGROWTH HORMONE-RELEASING HORMONE RECEPTOR, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordssignaling protein, receptor, membrane protein
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCell membrane; Multi-pass membrane protein Q02643
Total number of polymer chains2
Total molecular weight20249.43
Authors
Primary citation
Pike, A.C.W.,Quigley, A.,Barr, A.J.,Burgess Brown, N.,Shrestha, L.,Yang, J.,Chaikuad, A.,Vollmar, M.,Muniz, J.R.C.,von Delft, F.,Edwards, A.,Arrowsmith, C.H.,Weigelt, J.,Bountra, C.,Carpenter, E.P.
Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21360.6%2.1%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2xdg
no rotation
Molmil generated image of 2xdg
rotated about x axis by 90°
Molmil generated image of 2xdg
rotated about y axis by 90°