2X7F

Crystal structure of the kinase domain of human Traf2- and Nck- interacting Kinase with Wee1Chk1 inhibitor

2X7F の概要

• エントリーDOI: 10.2210/pdb2x7f/pdb
• 分子名称: TRAF2 AND NCK-INTERACTING PROTEIN KINASE, 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: serine/threonine-protein kinase, phosphoprotein, kinase, transferase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Nucleus: Q9UKE5
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 187959.49

構造登録者

Vollmar, M.,Alfano, I.,Shrestha, B.,Bray, J.,Muniz, J.R.C.,Roos, A.,Filippakopoulos, P.,Burgess-Brown, N.,Ugochukwu, E.,Gileadi, O.,Phillips, C.,Mahajan, P.,Pike, A.C.W.,Fedorov, O.,Chaikuad, A.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Knapp, S. (登録日: 2010-02-26, 公開日: 2010-07-14, 最終更新日: 2023-12-20)

• 主引用文献: Vollmar, M.,Alfano, I.,Shrestha, B.,Bray, J.,Muniz, J.R.C.,Roos, A.,Filippakopoulos, P.,Burgess-Brown, N.,Ugochukwu, E.,Gileadi, O.,Phillips, C.,Mahajan, P.,Pike, A.C.W.,Fedorov, O.,Chaikuad, A.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Knapp, S.; Crystal Structure of the Kinase Domain of Human Traf2- and Nck-Interacting Kinase with Wee1Chk1 Inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.8 Å)