2X6S

Human foamy virus integrase - catalytic core. Magnesium-bound structure.

2X6S の概要

• エントリーDOI: 10.2210/pdb2x6s/pdb
• 関連するPDBエントリー: 2X6N 2X74 2X78
• 分子名称: INTEGRASE, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: viral protein, retroviral integrase, dna-directed dna polymerase, nucleotidyltransferase, dna integration, aspartyl protease, dna recombination, transferase, nuclease, hydrolase
• 由来する生物種: HUMAN SPUMARETROVIRUS
• 細胞内の位置: Integrase: Virion (Potential). Protease/Reverse transcriptase/ribonuclease H: Host nucleus (By similarity): P14350
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 135612.61

構造登録者

Rety, S.,Delelis, O.,Rezabkova, L.,Dubanchet, B.,Silhan, J.,Lewit-Bentley, A. (登録日: 2010-02-19, 公開日: 2010-08-11, 最終更新日: 2023-12-20)

• 主引用文献: Rety, S.,Rezabkova, L.,Dubanchet, B.,Silhan, J.,Legrand, P.,Lewit-Bentley, A.; Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase; Acta Crystallogr.,Sect.F, 66:881-, 2010; PubMed: 20693659; DOI: 10.1107/S1744309110022852

実験手法

X-RAY DIFFRACTION (2.29 Å)