2X5Y

Human ZC3HAV1 (ARTD13), C-terminal domain

Summary for 2X5Y

Entry DOI	10.2210/pdb2x5y/pdb
Descriptor	ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 (2 entities in total)
Functional Keywords	antiviral defense, immune system, transferase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Isoform 1: Cytoplasm. Isoform 2: Cytoplasm: Q7Z2W4
Total number of polymer chains	1
Total formula weight	20309.09
Authors	Karlberg, T.,Schutz, P.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Kraulis, P.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Siponen, M.I.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H. (deposition date: 2010-02-11, release date: 2010-03-02, Last modification date: 2023-12-20)
Primary citation	Karlberg, T.,Klepsch, M.,Thorsell, A.,Andersson, C.D.,Linusson, A.,Schuler, H. Structural Basis for Lack of Adp-Ribosyltransferase Activity in Poly(Adp-Ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290:7336-, 2015 Cited by PubMed: 25635049 DOI: 10.1074/JBC.M114.630160 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.05 Å)

Structure validation