2WY3

Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands

2WY3 の概要

• エントリーDOI: 10.2210/pdb2wy3/pdb
• 関連するPDBエントリー: 1JE6
• 分子名称: MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE B, UNCHARACTERIZED PROTEIN UL16, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, ... (6 entities in total)
• 機能のキーワード: immune system-viral protein complex, immune response, innate immunity, structural mimicry, immunoglobulin domain, membrane, cytolysis, ulbp, nkg2d, nk cell, cell membrane, transmembrane, viral immune evasion, natural killer cell, convergent evolution, immune system/viral protein
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 114523.54

構造登録者

Mueller, S.,Zocher, G.,Steinle, A.,Stehle, T. (登録日: 2009-11-11, 公開日: 2010-02-02, 最終更新日: 2023-12-20)

• 主引用文献: Muller, S.,Zocher, G.,Steinle, A.,Stehle, T.; Structure of the Hcmv Ul16-Micb Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse Nkg2D Ligands.; Plos Pathog., 6:723-, 2010; PubMed: 20090832; DOI: 10.1371/JOURNAL.PPAT.1000723

実験手法

X-RAY DIFFRACTION (1.8 Å)