2WWF

Plasmodium falciparum thymidylate kinase in complex with TMP and ADP

Summary for 2WWF

Entry DOI	10.2210/pdb2wwf/pdb
Related	2WWG 2WWH 2WWI
Descriptor	THYMIDILATE KINASE, PUTATIVE, THYMIDINE-5'-PHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	transferase, kinase, malaria
Biological source	PLASMODIUM FALCIPARUM
Total number of polymer chains	3
Total formula weight	78088.98
Authors	Whittingham, J.L.,Carrero-Lerida, J.,Brannigan, J.A.,Ruiz-Perez, L.M.,Silva, A.P.G.,Fogg, M.J.,Wilkinson, A.J.,Gilbert, I.H.,Wilson, K.S.,Gonzalez-Pacanowska, D. (deposition date: 2009-10-23, release date: 2010-04-21, Last modification date: 2023-12-20)
Primary citation	Whittingham, J.L.,Carrero-Lerida, J.,Brannigan, J.A.,Ruiz-Perez, L.M.,Silva, A.P.G.,Fogg, M.J.,Wilkinson, A.J.,Gilbert, I.H.,Wilson, K.S.,Gonzalez-Pacanowska, D. Structural Basis for the Efficient Phosphorylation of Aztmp and Dgmp by Plasmodium Falciparum Type I Thymidylate Kinase. Biochem.J., 428:499-, 2010 Cited by PubMed: 20353400 DOI: 10.1042/BJ20091880 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation