2WVI

Crystal Structure of the N-terminal Domain of BubR1

2WVI の概要

• エントリーDOI: 10.2210/pdb2wvi/pdb
• 分子名称: MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 BETA, PRASEODYMIUM ION, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: tumor suppressor, mitotic checkpoint, tpr, kinase, apoptosis, serine/threonine-protein kinase, cell division, cell cycle, kinetochore, transferase, cytoskeleton
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cytoplasm: O60566
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20062.68

構造登録者

D'Arcy, S.,Davies, O.R.,Blundell, T.L.,Bolanos-Garcia, V.M. (登録日: 2009-10-16, 公開日: 2010-03-09, 最終更新日: 2011-07-13)

• 主引用文献: D'Arcy, S.,Davies, O.R.,Blundell, T.L.,Bolanos-Garcia, V.M.; Defining the Molecular Basis of Bubr1 Kinetochore Interactions and Anaphase-Promoting Complex/Cyclosome (Apc/C)-Cdc20 Inhibition; J.Biol.Chem., 285:14764-, 2010; PubMed: 20220147; DOI: 10.1074/JBC.M109.082016

実験手法

X-RAY DIFFRACTION (1.8 Å)