2WUE
Crystal structure of S114A mutant of HsaD from Mycobacterium tuberculosis in complex with HOPODA
Summary for 2WUE
| Entry DOI | 10.2210/pdb2wue/pdb |
| Related | 2VF2 2WUD 2WUF 2WUG |
| Descriptor | 2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE BPHD, THIOCYANATE ION, (3E,5R)-8-(2-CHLOROPHENYL)-5-METHYL-2,6-DIOXOOCT-3-ENOATE, ... (4 entities in total) |
| Functional Keywords | hydrolase |
| Biological source | MYCOBACTERIUM TUBERCULOSIS |
| Total number of polymer chains | 2 |
| Total formula weight | 64208.66 |
| Authors | Lack, N.A.,Yam, K.C.,Lowe, E.D.,Horsman, G.P.,Owen, R.,Sim, E.,Eltis, L.D. (deposition date: 2009-10-02, release date: 2009-10-20, Last modification date: 2023-12-20) |
| Primary citation | Lack, N.A.,Yam, K.C.,Lowe, E.D.,Horsman, G.P.,Owen, R.L.,Sim, E.,Eltis, L.D. Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism. J. Biol. Chem., 285:434-443, 2010 Cited by PubMed: 19875455DOI: 10.1074/jbc.M109.058081 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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