2WQN

Structure of ADP-bound human Nek7

2WQN の概要

• エントリーDOI: 10.2210/pdb2wqn/pdb
• 関連するPDBエントリー: 2WQM 2WQO
• 分子名称: SERINE/THREONINE-PROTEIN KINASE NEK7, ADENOSINE-5'-DIPHOSPHATE, NICKEL (II) ION, ... (6 entities in total)
• 機能のキーワード: atp-binding, polymorphism, metal-binding, serine/threonine-protein kinase, mitosis, cytoplasm, transferase, phosphoprotein, protein kinase, nucleotide-binding
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36276.38

構造登録者

Richards, M.W.,Bayliss, R. (登録日: 2009-08-24, 公開日: 2009-12-08, 最終更新日: 2023-12-20)

• 主引用文献: Richards, M.W.,O'Regan, L.,Mas-Droux, C.,Blot, J.M.,Cheung, J.,Hoelder, S.,Fry, A.M.,Bayliss, R.; An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated Nek7 Kinase is Released Through Binding of Nek9.; Mol.Cell, 36:560-, 2009; PubMed: 19941817; DOI: 10.1016/J.MOLCEL.2009.09.038

実験手法

X-RAY DIFFRACTION (2.3 Å)