2WNL

CRYSTAL STRUCTURE OF APLYSIA ACHBP IN COMPLEX WITH ANABASEINE

Summary for 2WNL

Related2WN9 2W8F 2BR8 2BR7 2BYR 2BYP 2BYS 2BYN 2C9T 2W8E 2BYQ 2WNJ 2W8G 2WNC 2UZ6
DescriptorSOLUBLE ACETYLCHOLINE RECEPTOR, 3,4,5,6-tetrahydro-2,3'-bipyridine, 5-amino-1-pyridin-3-ylpentan-1-one, ... (7 entities in total)
Functional Keywordsreceptor, anabaseine, acetylcholine binding protein
Biological sourceAPLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
Total number of polymer chains10
Total molecular weight260972.21
Authors
Sulzenbacher, G.,Hibbs, R.,Shi, J.,Talley, T.,Conrod, S.,Kem, W.,Taylor, P.,Marchot, P.,Bourne, Y. (deposition date: 2009-07-09, release date: 2009-09-01, Last modification date: 2019-04-03)
Primary citation
Hibbs, R.E.,Sulzenbacher, G.,Shi, J.,Talley, T.T.,Conrod, S.,Kem, W.R.,Taylor, P.,Marchot, P.,Bourne, Y.
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
EMBO J., 28:3040-3051, 2009
PubMed: 19696737 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2009.227
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25640 4.4% 1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution