2WNB

Crystal Structure of a Mammalian Sialyltransferase in complex with disaccharide and CMP

Summary for 2WNB

Entry DOI	10.2210/pdb2wnb/pdb
Related	2WML 2WNF
Related PRD ID	PRD_900084
Descriptor	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, CYTIDINE-5'-MONOPHOSPHATE, ... (5 entities in total)
Functional Keywords	glycosyltransferase, alternative splicing, disulfide bond, golgi apparatus, sialyltransferase, glycoprotein, signal-anchor, transmembrane, membrane, secreted, transferase, sialic acid
Biological source	Sus scrofa (pig)
Cellular location	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: Q02745
Total number of polymer chains	1
Total formula weight	35594.61
Authors	Rao, F.V.,Rich, J.R.,Raikic, B.,Wakarchuk, W.W.,Withers, S.G.,Strynadka, N.C.J. (deposition date: 2009-07-08, release date: 2009-10-13, Last modification date: 2023-12-13)
Primary citation	Rao, F.V.,Rich, J.R.,Rakic, B.,Buddai, S.,Schwartz, M.F.,Johnson, K.,Bowe, C.,Wakarchuk, W.W.,Defrees, S.,Withers, S.G.,Strynadka, N.C.J. Structural Insight Into Mammalian Sialyltransferases. Nat.Struct.Mol.Biol., 16:1186-, 2009 Cited by PubMed: 19820709 DOI: 10.1038/NSMB.1685 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation